产品货号：
Z21766
中文名称：
Neurturin/NRTN抗体
英文名称：
Anti-Neurturin/NRTN Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Neurturin/NRTN Antibody |
| 指标别名 | NTN;Neurturin |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | NRTN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Neurturin antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Neurturin.The immunogen is located within the last 50 amino acids of Neurturin. |
| 计算分子量 | 22kDa |
| 成分 | Neurturin Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Neurturin Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation.A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin.Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha.The cDNAs encoding NTNRalpha from human,rat,chicken,and mouse have been cloned recently and termed GDNFR汕，Ret ligand 2 (RETL2) or TGF-beta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFR汐-2 recently.NTN binds to and forms a complex with GFR汐-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway.Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations.Neurturin and GDNF define a new family of neurotrophic factors. |
| Uniprot ID | Q99748 |
| 基因名全称 | Neurturin |
| 蛋白名全称 | Neurturin |
| 推荐稀释比 | Neurturin antibody can be used for detection of neurturin by Western blot.An approximate 14kDa band of the full length recombinant NTN was detected.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 5μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples.All other applications and species not yet tested. |
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